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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNN2 All Species: 22.42
Human Site: Y184 Identified Species: 41.11
UniProt: Q99439 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99439 NP_004359.1 309 33697 Y184 S Q S G M T A Y G T R R H L Y
Chimpanzee Pan troglodytes XP_001156976 309 33707 Y184 S Q S G M T A Y G T R R H L Y
Rhesus Macaque Macaca mulatta XP_001110773 309 33749 Y184 S Q S G M T A Y G T R R H L Y
Dog Lupus familis XP_854646 309 33368 Y184 S Q S G M T A Y G T R R H L Y
Cat Felis silvestris
Mouse Mus musculus Q08093 305 33137 M181 K C A S Q S G M T A Y G T R R
Rat Rattus norvegicus P37397 330 36416 K197 D P K M Q T D K P F D Q T T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521357 371 41328 Y224 S Q A G M T A Y G T R R H L Y
Chicken Gallus gallus P26932 292 32342 M168 R N I I G L Q M G T N K F A S
Frog Xenopus laevis NP_001085881 295 32821 T171 V I G L Q M G T N K C A S Q S
Zebra Danio Brachydanio rerio NP_998514 307 33822 Y183 S Q A G M N A Y G T R R H L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14318 184 20172 P60 K L I N V L S P N A V P K V N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P37806 565 62709 E362 G F G T G R R E T T K M V D S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08873 200 22730 N76 E A D T G E A N H I S W K S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 94.5 N.A. 94.8 63.3 N.A. 54.7 58.2 78.6 72.8 N.A. 23.2 N.A. 21.7 N.A.
Protein Similarity: 100 100 98.3 95.1 N.A. 95.7 74.2 N.A. 64.6 72.8 85.1 81.2 N.A. 36.5 N.A. 33 N.A.
P-Site Identity: 100 100 100 100 N.A. 0 6.6 N.A. 93.3 13.3 0 86.6 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 13.3 N.A. 100 20 0 93.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 24 0 0 0 54 0 0 16 0 8 0 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 8 0 0 0 8 0 0 8 0 % D
% Glu: 8 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 8 0 16 47 24 0 16 0 54 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 47 0 0 % H
% Ile: 0 8 16 8 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 16 0 8 0 0 0 0 8 0 8 8 8 16 0 0 % K
% Leu: 0 8 0 8 0 16 0 0 0 0 0 0 0 47 0 % L
% Met: 0 0 0 8 47 8 0 16 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 8 0 8 0 8 16 0 8 0 0 0 8 % N
% Pro: 0 8 0 0 0 0 0 8 8 0 0 8 0 0 0 % P
% Gln: 0 47 0 0 24 0 8 0 0 0 0 8 0 8 0 % Q
% Arg: 8 0 0 0 0 8 8 0 0 0 47 47 0 8 8 % R
% Ser: 47 0 31 8 0 8 8 0 0 0 8 0 8 8 31 % S
% Thr: 0 0 0 16 0 47 0 8 16 62 0 0 16 8 0 % T
% Val: 8 0 0 0 8 0 0 0 0 0 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 0 0 8 0 0 0 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _